KMID : 0880220070450010075
|
|
Journal of Microbiology 2007 Volume.45 No. 1 p.75 ~ p.78
|
|
Analysis of Substitution Events in HIV-1 vif Gene of the Korean Clade
|
|
Park Chan-Seung
Kim Mi-Suk Yi Hyun-Ah Lee Dong-Hun Lee Keon-Myung Lee Chan-Hee
|
|
Abstract
|
|
|
Nucleotide and amino acid substitution pattern in vif gene of the Korean clade of HIV-1 isolated from Koreans were analyzed using consensus sequences. At nucleotide level, transition/transversion substitution ratio was 1.88, and nonsynonymous/synonymous substitution ratio was 2.67, suggesting a divergent evolution in the Korean clade. At amino acid level, there were 17 substitutions and G¡æE substitution at position 37 may be responsible for change in predicted secondary structure.
|
|
KEYWORD
|
|
HIV-1, vif, Korean clade, substitution ratio
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|